ZNF778

Across TCGA patient cohorts, ZNF778 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,150 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF778-associated proteins across cancer lineages are DYNLL2, YTHDC1, and CKAP4_S26. Each is linked with ZNF778 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF778-to-partner and partner-to-ZNF778 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF778 versus DYNLL2 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF778→partner) and Y-score (partner→ZNF778) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DYNLL2 →	+0.411	+0.366	<.001	.006	3	5
GBM	YTHDC1 →	+0.355	+0.374	<.001	<.001	3	5
LSCC	CKAP4_S26 →	-0.588	-0.481	<.001	<.001	3	4
LUAD	EIF4B →	-0.235	-0.338	.002	.005	3	4
GBM	FTO →	+0.328	+0.300	<.001	<.001	3	4
GBM	DDX39B →	+0.198	+0.349	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,150 associations by consensus.

ZNF778 vs DYNLL2 — HNSC

Explore this scatter interactively →