ZNF776

Across TCGA patient cohorts, ZNF776 mutation is significantly associated with the RNA expression of many other genes, with 3,010 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF776-associated genes across cancer lineages are RN7SKP181, THRSP, and RNA5SP414. Each is linked with ZNF776 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF776-to-partner and partner-to-ZNF776 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP181 grouped by ZNF776-low versus ZNF776-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF776→partner) and Y-score (partner→ZNF776) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP181 →	+0.114	+4.685	<.001	.007	3	3
UCEC	THRSP →	+0.536	+1.893	.003	<.001	3	2
UCEC	RNA5SP414 →	+0.548	+2.053	<.001	<.001	3	2
LUSC	RN7SL314P →	+0.093	+3.370	.005	.008	3	2
LUSC	MIR4637 →	+0.572	+3.066	<.001	.008	3	2
UCEC	RNA5SP417 →	+0.529	+2.351	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,010 associations by consensus.

RN7SKP181 by ZNF776 expression — BLCA

Explore this box plot interactively →