ZNF776

Across TCGA cell cohorts, ZNF776 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,755 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF776-associated GO terms across cancer lineages are Protein sumoylation, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with ZNF776 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF776-to-partner and partner-to-ZNF776 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein sumoylation grouped by ZNF776-low versus ZNF776-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF776→partner) and Y-score (partner→ZNF776) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein sumoylation →	+0.104	+1.096	<.001	<.001	3	17
OVARY	Regulation of myoblast fusion →	+0.104	+0.888	<.001	<.001	3	16
OVARY	Negative regulation of myoblast fusion →	+0.114	+0.935	<.001	<.001	3	16
SOFT_TISSUE	Regulation of DNA-templated transcription initiation →	+0.059	+0.554	<.001	.002	3	16
STOMACH	Protein polyubiquitination →	+0.070	+1.213	<.001	.001	3	16
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.112	+0.935	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,755 associations by consensus.

Protein sumoylation by ZNF776 expression — LUNG_SCLC

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