ZNF767P

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF767P mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF767P-associated genes across cancer lineages are MEK1, PDCD4, and PDK1_pS241. Each is linked with ZNF767P in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF767P-to-partner and partner-to-ZNF767P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by ZNF767P-low versus ZNF767P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF767P→partner) and Y-score (partner→ZNF767P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEK1 →+0.450+3.321.018.01031
UCECPDCD4 →-0.904-2.999<.001.03531
UCECPDK1_pS241 →+0.254+2.183.004.03531
UCECPDK1 →+0.117+3.000.038.03621
UCECTIGAR →+0.246+2.196.002.03421
UCEC4E-BP1_pT37_T46 →-0.575-3.321.003.01021
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MEK1 by ZNF767P expression — UCEC

Box plot of MEK1 in ZNF767P-low vs ZNF767P-high samples in UCEC.

Explore this box plot interactively →

Exploration