ZNF76

Across TCGA cell cohorts, ZNF76 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF76-associated genes across cancer lineages are CABP2, ENPP6, and CD300H. Each is linked with ZNF76 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF76-to-partner and partner-to-ZNF76 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CABP2 grouped by ZNF76-low versus ZNF76-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF76→partner) and Y-score (partner→ZNF76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CABP2 →	+0.023	+4.906	<.001	.006	3	1
LARGE_INTESTINE	ENPP6 →	+0.029	+3.115	.006	.004	3	1
LARGE_INTESTINE	CD300H →	+0.031	+4.000	<.001	<.001	3	1
BLOOD_Leukemia	LGI1 →	+0.079	+5.124	<.001	<.001	3	1
BLOOD_Leukemia	PRKAG3 →	+0.035	+3.551	<.001	.009	3	1
BLOOD_Leukemia	MAGEB4 →	+0.037	+3.705	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

CABP2 by ZNF76 expression — OESOPHAGUS

Explore this box plot interactively →