ZNF750

Across TCGA cell cohorts, ZNF750 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF750-associated genes across cancer lineages are C10orf53, ACTRT1, and OR5P3. Each is linked with ZNF750 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF750-to-partner and partner-to-ZNF750 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by ZNF750-low versus ZNF750-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF750→partner) and Y-score (partner→ZNF750) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	C10orf53 →	+0.023	+4.906	<.001	.006	3	1
BLOOD_Leukemia	ACTRT1 →	+0.021	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR5P3 →	+0.125	+5.201	<.001	.006	3	1
BLOOD_Leukemia	FAM9A →	+0.019	+5.539	<.001	.003	3	1
BLOOD_Leukemia	OR6C70 →	+0.025	+4.922	<.001	.009	3	1
BLOOD_Leukemia	TEX43 →	+0.141	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

C10orf53 by ZNF750 expression — OESOPHAGUS

Explore this box plot interactively →