ZNF747

Across TCGA patient cohorts, ZNF747 mutation is significantly associated with the RNA expression of many other genes, with 508 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF747-associated genes across cancer lineages are PRAMEF7, RNU7-97P, and MIR4717. Each is linked with ZNF747 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF747-to-partner and partner-to-ZNF747 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF7 grouped by ZNF747-low versus ZNF747-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF747→partner) and Y-score (partner→ZNF747) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRAMEF7 →	+0.141	+2.582	.002	.001	3	2
UCEC	RNU7-97P →	+0.358	+2.496	<.001	.008	3	2
HNSC	MIR4717 →	+0.441	+5.111	<.001	.004	3	2
LUSC	RNU6-1059P →	+0.217	+7.924	<.001	.008	3	2
HNSC	OR2A4 →	+0.071	+4.372	<.001	.007	3	1
HNSC	RNU6-79P →	+0.801	+5.063	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 508 associations by consensus.

PRAMEF7 by ZNF747 expression — UCEC

Explore this box plot interactively →