ZNF747

Across TCGA pan-cancer cohorts, ZNF747 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ZNF747 data layer compared with 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher ZNF747 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF747 expression acts as an unfavorable survival marker, although some lineages such as LUSC and KIRC show a favorable association.

LUSC, KIRC, and BRCA are the cancer types where ZNF747 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Quartile	All	0.847	0.698	<.001	60	view →
KIRC	DFS	Median	All	0.751	0.485	<.001	56	view →
BRCA	OS	Tertile	All	0.984	0.942	.001	48	view →
CESC	OS	Tertile	All	0.928	0.814	.004	26	view →
PAAD	DFS	Quartile	All	0.392	0.206	.011	24	view →
OV	OS	Tertile	All	0.882	0.791	.016	20	view →
UVM	OS	Median	III,IV	0.873	0.491	.007	20	view →
LIHC	DFS	Quartile	All	0.447	0.623	.006	19	view →
KIRP	DFS	Median	IV	0.037	0.526	.010	16	view →
LGG	OS	Median	All	0.865	0.924	.009	11	view →
THYM	DFS	Tertile	All	0.845	0.426	.017	10	view →
ACC	DFS	Median	All	0.308	0.709	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ZNF747–LUSC (OS)

Open the LUSC breakdown →