ZNF747

Across TCGA patient cohorts, ZNF747 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF747-associated genes across cancer lineages are 14-3-3_beta, eEF2, and eIF4E. Each is linked with ZNF747 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF747-to-partner and partner-to-ZNF747 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by ZNF747-low versus ZNF747-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF747→partner) and Y-score (partner→ZNF747) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.116	-2.973	.013	.035	3	1
UCEC	eEF2 →	+0.492	+2.999	.003	.035	3	1
UCEC	eIF4E →	+0.260	+3.321	.008	.010	3	1
UCEC	FOXO3a_pS318_S321 →	-0.144	-2.312	.013	.034	3	1
UCEC	GAPDH →	+0.660	+3.321	.008	.009	3	1
UCEC	GATA6 →	-0.223	-2.452	.002	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

14-3-3_beta by ZNF747 expression — UCEC

Explore this box plot interactively →