ZNF747

Across TCGA cell cohorts, ZNF747 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,549 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF747-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, CAMP/PKA signal transduction, and Autophagosome maturation. Each is linked with ZNF747 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF747-to-partner and partner-to-ZNF747 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by ZNF747-low versus ZNF747-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF747→partner) and Y-score (partner→ZNF747) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.123	+0.551	<.001	.007	3	10
BLOOD_Lymphoma	CAMP/PKA signal transduction →	+0.121	+0.605	<.001	<.001	3	9
KIDNEY	Autophagosome maturation →	+0.059	+1.043	.005	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.098	-0.729	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.103	-0.691	<.001	<.001	3	9
KIDNEY	Positive regulation of macrophage proliferation →	+0.221	+1.117	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,549 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by ZNF747 expression — UPPER_AERODIGESTIVE_TRACT

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