Across TCGA patient cohorts, ZNF74 protein abundance is significantly associated with the RNA expression of many other genes, with 2,981 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF74-associated genes across cancer lineages are CADM4, NUP93, and COMTD1. Each is linked with ZNF74 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF74-to-partner and partner-to-ZNF74 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF74→partner) and Y-score (partner→ZNF74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CADM4 →	+1.446	+1.587	.002	.002	3	3
OV	NUP93 →	-0.744	-0.718	.003	.006	3	2
OV	COMTD1 →	+1.357	+0.824	.001	.003	3	2
OV	STAT3 →	-1.245	-1.199	<.001	.002	3	2
OV	PTPRM →	-1.206	-0.860	.003	<.001	3	2
OV	SPRY4 →	-2.229	-1.286	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,981 associations by consensus.

Exploration

ZNF74 survival (RNA) · tumor vs normal (RNA) · all ZNF74 data types