ZNF725P

Across TCGA pan-cancer cohorts, ZNF725P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ZNF725P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ZNF725P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF725P expression acts as an unfavorable survival marker, although some lineages such as LIHC and GBM show a favorable association.

UVM, KIRC, and READ are the cancer types where ZNF725P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.234	0.866	<.001	99	view →
KIRC	DFS	Tertile	III,IV	0.215	0.531	.001	75	view →
READ	OS	Tertile	IV	0.334	0.918	<.001	54	view →
MESO	OS	Tertile	II,III,IV	0.282	0.588	.021	36	view →
KICH	OS	Tertile	All	0.635	0.936	.010	21	view →
THCA	OS	Tertile	IV	0.601	0.975	.012	18	view →
LIHC	DFS	Tertile	All	0.655	0.370	.009	18	view →
THYM	OS	Tertile	All	0.700	0.974	.003	15	view →
HNSC	OS	Tertile	III,IV	0.669	0.745	.024	12	view →
STAD	DFS	Median	II,III,IV	0.474	0.592	.019	12	view →
LUAD	DFS	Tertile	IV	0.416	0.749	.030	12	view →
GBM	OS	Median	All	0.335	0.217	.006	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ZNF725P–UVM (OS)

Open the UVM breakdown →