Q-omics provides the consensus-scored ZNF725P profile across patient tissues and cancer cell-line models. ZNF725P expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, ZNF725P is differentially expressed in 8, with the highest sampling consensus in COAD. Additionally, ZNF725P RNA expression shows 6,936 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UVM, COAD, and STAD as cancer lineages where ZNF725P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF725P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF725P survival associations across molecular data types. ZNF725P RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF725P RNA expression–survival associations across cancer types. High ZNF725P expression shows unfavorable associations in UVM, KIRC, READ, MESO, KICH and THCA. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for ZNF725P RNA expression.
This table summarizes ZNF725P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for ZNF725P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF725P shows lower tumor expression in COAD, READ, KIRC and STAD and higher tumor expression in BRCA and BLCA. The COAD box plot shows higher ZNF725P RNA expression in normal versus tumor tissue (log2 FC = −0.062, t-test p < 0.001).
This table shows molecular features associated with ZNF725P in patient tissues and cancer cell lines. In patient samples, ZNF725P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
