Across TCGA cell cohorts, ZNF721 mutation is significantly associated with the RNA expression of many other genes, with 104 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF721-associated genes across cancer lineages are TSSK1B, GSTT4, and POTEB3. Each is linked with ZNF721 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF721-to-partner and partner-to-ZNF721 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF721→partner) and Y-score (partner→ZNF721) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TSSK1B →	+0.007	+3.289	.001	.009	3	2
OVARY	GSTT4 →	+0.075	+4.000	<.001	.004	3	2
OESOPHAGUS	POTEB3 →	+0.029	+4.017	.001	.007	3	1
SKIN	TINAG →	+0.172	+3.678	.002	.009	3	1
STOMACH	TRIM49D2 →	+0.040	+5.285	<.001	.003	3	1
LARGE_INTESTINE	CRBN →	+0.379	+3.251	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 104 associations by consensus.

Exploration

ZNF721 survival (RNA) · tumor vs normal (RNA) · all ZNF721 data types