ZNF710-AS1

Across TCGA pan-cancer cohorts, ZNF710-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ZNF710-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ZNF710-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF710-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, UCS, and KIRP are the cancer types where ZNF710-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	II,III,IV	0.784	0.594	<.001	106	view →
UCS	DFS	Tertile	III,IV	0.627	0.188	.003	70	view →
KIRP	OS	Tertile	All	0.863	0.549	<.001	68	view →
ACC	DFS	Tertile	All	0.310	0.741	.002	46	view →
PAAD	OS	Median	All	0.511	0.291	<.001	45	view →
UVM	DFS	Quartile	II,III,IV	0.354	0.734	.006	36	view →
ESCA	DFS	Median	All	0.322	0.905	.005	23	view →
COAD	OS	Median	IV	0.300	0.841	.002	22	view →
LGG	OS	Median	All	0.935	0.858	<.001	18	view →
SKCM	DFS	Quartile	II,III,IV	0.714	0.580	.003	14	view →
THYM	OS	Median	All	0.952	0.776	.007	14	view →
LIHC	DFS	Median	II,III,IV	0.307	0.500	.013	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ZNF710-AS1–HNSC (DFS)

Open the HNSC breakdown →