ZNF710-AS1

Across TCGA pan-cancer cohorts, ZNF710-AS1 RNA differs between tumor and matched normal tissue in 18 of 18 cancer types tested, making tumor–normal expression one of ZNF710-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ZNF710-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF710-AS1 is over-expressed in tumor, although a few such as HNSC and KIRP show the opposite, repressed pattern.

HNSC, KIRP, and BLCA are the cancer types where ZNF710-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF710-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	−1.679	<.001	12	view →
KIRP	Male	III,IV	−2.977	<.001	11	view →
BLCA	Male	IV	−3.645	<.001	10	view →
THCA	Male	III,IV	−1.250	<.001	10	view →
KIRC	Male	All	−1.585	<.001	8	view →
LIHC	All	All	+0.595	<.001	8	view →
COAD	All	All	−0.771	<.001	7	view →
UCEC	All	II,III,IV	−1.202	<.001	6	view →
BRCA	All	III,IV	−1.011	<.001	6	view →
LUSC	Male	All	−0.560	<.001	5	view →
PAAD	Female	All	−0.944	.003	4	view →
LUAD	Female	II,III,IV	−0.824	.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 18 lineages.

ZNF710-AS1–HNSC

Open the HNSC breakdown →