ZNF709

Across TCGA patient cohorts, ZNF709 mutation is significantly associated with the RNA expression of many other genes, with 3,188 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF709-associated genes across cancer lineages are LINC02085, SRSF6P1, and MIR3135A. Each is linked with ZNF709 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF709-to-partner and partner-to-ZNF709 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02085 grouped by ZNF709-low versus ZNF709-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF709→partner) and Y-score (partner→ZNF709) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02085 →	+0.192	+2.308	.002	.002	3	3
LIHC	SRSF6P1 →	+0.268	+6.169	<.001	<.001	3	3
LUSC	MIR3135A →	+0.431	+2.998	<.001	.003	3	3
UCEC	MTFP1 →	+0.537	+2.534	<.001	<.001	3	3
UCEC	MCM5 →	+0.458	+2.523	.001	<.001	3	3
SKCM	GMNN →	+0.557	+2.421	.009	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,188 associations by consensus.

LINC02085 by ZNF709 expression — SKCM

Explore this box plot interactively →