ZNF709

Across TCGA cell cohorts, ZNF709 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,352 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF709-associated GO terms across cancer lineages are Positive regulation of stem cell population maintenance, Regulation of cytoplasmic mRNA processing body assembly, and Positive regulation of organelle assembly. Each is linked with ZNF709 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF709-to-partner and partner-to-ZNF709 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stem cell population maintenance grouped by ZNF709-low versus ZNF709-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF709→partner) and Y-score (partner→ZNF709) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of stem cell population maintenance →	+0.078	+0.665	<.001	<.001	3	14
BLOOD_Leukemia	Regulation of cytoplasmic mRNA processing body assembly →	+0.126	+0.756	<.001	<.001	3	13
STOMACH	Positive regulation of organelle assembly →	+0.076	+0.752	<.001	<.001	3	13
BONE	Positive regulation of double-strand break repair →	+0.092	+0.677	<.001	.006	3	13
LUNG_SCLC	Regulation of transcription initiation by RNA polymerase II →	+0.074	+0.685	<.001	<.001	3	12
BONE	Protein-DNA complex organization →	+0.101	+0.625	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,352 associations by consensus.

Positive regulation of stem cell population maintenance by ZNF709 expression — LUNG_SCLC

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