ZNF705A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF705A mutation is significantly associated with the RNA expression of many other genes, with 4,967 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF705A-associated genes across cancer lineages are BRI3, KATNAL2, and SLC3A2. Each is linked with ZNF705A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF705A-to-partner and partner-to-ZNF705A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF705A→partner) and Y-score (partner→ZNF705A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMBRI3 →+0.410+3.350.007.00532
UCECKATNAL2 →-0.769-2.989<.001<.00132
UCECSLC3A2 →+0.708+2.850<.001<.00132
SKCMIP6K1 →+0.386+2.172.009.00932
SKCMMX2 →-1.292-3.900.001<.00132
UCECPNMA3 →-1.045-2.783.004.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,967 associations by consensus.

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