ZNF704

Across TCGA cell cohorts, ZNF704 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,259 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNF704-associated GO terms across cancer lineages are Response to hydroxyurea, Regulation of nucleotide-excision repair, and Positive regulation of DNA repair. Each is linked with ZNF704 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF704-to-partner and partner-to-ZNF704 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to hydroxyurea grouped by ZNF704-low versus ZNF704-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF704→partner) and Y-score (partner→ZNF704) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Response to hydroxyurea →	+0.137	+2.549	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of nucleotide-excision repair →	+0.100	+3.114	.005	<.001	3	11
SOFT_TISSUE	Positive regulation of DNA repair →	+0.072	+2.870	<.001	<.001	3	11
OVARY	Transcription initiation-coupled chromatin remodeling →	+0.091	+1.850	<.001	<.001	3	11
OVARY	Calcium ion transport →	-0.074	-1.702	<.001	<.001	3	10
LUNG_SCLC	Heterochromatin organization →	+0.069	+2.453	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,259 associations by consensus.

Response to hydroxyurea by ZNF704 expression — LUNG_SCLC

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