ZNF704

Across TCGA cell cohorts, ZNF704 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF704-associated genes across cancer lineages are C6orf118, MS4A7, and OR1L6. Each is linked with ZNF704 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF704-to-partner and partner-to-ZNF704 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by ZNF704-low versus ZNF704-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF704→partner) and Y-score (partner→ZNF704) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.132	+4.378	<.001	<.001	3	1
LARGE_INTESTINE	MS4A7 →	+0.037	+3.679	.001	.005	3	1
LARGE_INTESTINE	OR1L6 →	+0.015	+3.700	<.001	.009	3	1
LARGE_INTESTINE	ASCL3 →	+0.178	+3.617	<.001	.004	3	1
LARGE_INTESTINE	BPIFA1 →	+0.171	+3.103	<.001	.004	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.008	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

C6orf118 by ZNF704 expression — LARGE_INTESTINE

Explore this box plot interactively →