Across TCGA cell cohorts, ZNF703 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF703-associated genes across cancer lineages are SIAH3, BRDT, and KLHL40. Each is linked with ZNF703 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF703-to-partner and partner-to-ZNF703 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF703→partner) and Y-score (partner→ZNF703) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SIAH3 →	+0.042	+4.867	<.001	.009	3	2
BLOOD_Leukemia	BRDT →	+0.150	+4.342	<.001	.002	3	2
BLOOD_Lymphoma	KLHL40 →	+0.006	+5.209	.006	.005	3	1
BLOOD_Lymphoma	RNASE8 →	+0.044	+5.209	<.001	.005	3	1
LARGE_INTESTINE	TAFA1 →	+0.241	+4.009	.001	<.001	3	1
BLOOD_Leukemia	ITIH6 →	+0.028	+3.754	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

ZNF703 survival (RNA) · tumor vs normal (RNA) · all ZNF703 data types