ZNF701

Across TCGA cell cohorts, ZNF701 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF701-associated genes across cancer lineages are PROP1, TSSK1B, and OR1D4. Each is linked with ZNF701 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF701-to-partner and partner-to-ZNF701 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PROP1 grouped by ZNF701-low versus ZNF701-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF701→partner) and Y-score (partner→ZNF701) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PROP1 →	+0.032	+4.874	<.001	.002	3	1
BLOOD_Leukemia	TSSK1B →	+0.019	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR1D4 →	+0.046	+4.539	<.001	.007	3	1
LARGE_INTESTINE	FAM205A →	+0.022	+4.614	<.001	.002	3	1
LARGE_INTESTINE	CCDC179 →	+0.048	+3.510	.004	.003	3	1
SKIN	KRTAP4-11 →	+0.019	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

PROP1 by ZNF701 expression — BLOOD_Leukemia

Explore this box plot interactively →