Across TCGA patient cohorts, ZNF70 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF70-associated genes across cancer lineages are INPP4B, FoxM1, and JNK_pT183_Y185. Each is linked with ZNF70 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF70-to-partner and partner-to-ZNF70 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF70→partner) and Y-score (partner→ZNF70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.307	-3.584	.015	.002	3	2
UCEC	FoxM1 →	+0.222	+1.584	.029	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.150	-2.459	.023	.019	3	1
UCEC	JNK2 →	+0.273	+2.000	<.001	.010	3	1
UCEC	Ku80 →	+0.211	+2.009	.022	.017	3	1
UCEC	MEK1 →	+0.343	+2.321	.016	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

ZNF70 survival (RNA) · tumor vs normal (RNA) · all ZNF70 data types