Across TCGA cell cohorts, ZNF70 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF70-associated genes across cancer lineages are NPPB, GSC, and KIAA0319. Each is linked with ZNF70 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF70-to-partner and partner-to-ZNF70 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF70→partner) and Y-score (partner→ZNF70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NPPB →	+0.092	+3.662	<.001	.003	3	1
BLOOD_Leukemia	GSC →	+1.121	+2.948	<.001	.008	3	1
BLOOD_Leukemia	KIAA0319 →	+0.269	+3.378	<.001	.008	3	1
BLOOD_Leukemia	ZIC5 →	+0.493	+3.474	.003	.007	3	1
BLOOD_Leukemia	CPXCR1 →	+0.077	+4.234	<.001	<.001	3	1
BLOOD_Leukemia	NPFFR1 →	+0.011	+3.359	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

ZNF70 survival (RNA) · tumor vs normal (RNA) · all ZNF70 data types