ZNF697

Across TCGA patient cohorts, ZNF697 mutation is significantly associated with the RNA expression of many other genes, with 3,820 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF697-associated genes across cancer lineages are NPBWR2, ENPP7P3, and RN7SL98P. Each is linked with ZNF697 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF697-to-partner and partner-to-ZNF697 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPBWR2 grouped by ZNF697-low versus ZNF697-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF697→partner) and Y-score (partner→ZNF697) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	NPBWR2 →	+0.026	+3.273	<.001	.007	3	4
SKCM	ENPP7P3 →	+0.131	+3.669	.002	.006	3	3
UCEC	RN7SL98P →	+0.079	+1.906	.004	.007	3	3
UCEC	PLCB3 →	+0.393	+1.872	.002	.004	3	2
UCEC	NOCT →	+0.586	+2.095	<.001	.003	3	2
UCEC	AP1S3 →	+0.558	+4.000	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,820 associations by consensus.

NPBWR2 by ZNF697 expression — CESC

Explore this box plot interactively →