ZNF697

Across TCGA patient cohorts, ZNF697 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF697-associated genes across cancer lineages are TFRC, ATM, and Cyclin-B1. Each is linked with ZNF697 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF697-to-partner and partner-to-ZNF697 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by ZNF697-low versus ZNF697-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF697→partner) and Y-score (partner→ZNF697) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.475	+2.115	.013	.017	3	2
UCEC	ATM →	-0.463	-1.925	.004	.005	3	2
UCEC	Cyclin-B1 →	+0.707	+3.000	<.001	<.001	3	2
UCEC	14-3-3_beta →	-0.104	-2.195	.003	.009	3	1
UCEC	eIF4E →	+0.208	+2.906	.006	.001	3	1
UCEC	eIF4G →	+0.312	+3.700	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

TFRC by ZNF697 expression — UCEC

Explore this box plot interactively →