ZNF697

Across TCGA cell cohorts, ZNF697 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,269 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF697-associated GO terms across cancer lineages are Adenylate cyclase-activating serotonin receptor signaling pathway, Serotonin receptor signaling pathway, and Positive regulation of postsynaptic membrane organization. Each is linked with ZNF697 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF697-to-partner and partner-to-ZNF697 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adenylate cyclase-activating serotonin receptor signaling pathway grouped by ZNF697-low versus ZNF697-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF697→partner) and Y-score (partner→ZNF697) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Adenylate cyclase-activating serotonin receptor signaling pathway →	-0.296	-0.718	.004	.003	3	9
LUNG_NSCLC_LUSC	Serotonin receptor signaling pathway →	-0.180	-1.063	.002	.007	3	9
SKIN	Positive regulation of postsynaptic membrane organization →	+0.145	+1.254	.001	.001	3	8
SKIN	Positive regulation of AMPA glutamate receptor clustering →	+0.145	+1.254	.001	.001	3	8
CNS	Natural killer cell chemotaxis →	+0.958	+0.935	<.001	<.001	3	8
SKIN	Response to interleukin-3 →	+0.177	+1.302	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,269 associations by consensus.

Adenylate cyclase-activating serotonin receptor signaling pathway by ZNF697 expression — BLOOD_Lymphoma

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