ZNF697

Across TCGA cell cohorts, ZNF697 mutation is significantly associated with the RNA expression of many other genes, with 625 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF697-associated genes across cancer lineages are GGA1, HPS4, and GCAT. Each is linked with ZNF697 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF697-to-partner and partner-to-ZNF697 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GGA1 grouped by ZNF697-low versus ZNF697-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF697→partner) and Y-score (partner→ZNF697) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GGA1 →	+0.506	+2.743	.009	.001	3	1
LARGE_INTESTINE	HPS4 →	+0.585	+2.129	.001	.007	3	1
LARGE_INTESTINE	GCAT →	+0.954	+3.169	.008	.009	3	1
LARGE_INTESTINE	EIF3L →	+0.465	+3.257	.003	.002	3	1
LARGE_INTESTINE	HSCB →	+0.520	+3.169	.002	.006	3	1
LARGE_INTESTINE	CBY1 →	+0.665	+3.936	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 625 associations by consensus.

GGA1 by ZNF697 expression — LARGE_INTESTINE

Explore this box plot interactively →