ZNF691

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF691 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF691-associated genes across cancer lineages are Adipocytes, Eosinophils, and Th2 cells. Each is linked with ZNF691 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF691-to-partner and partner-to-ZNF691 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by ZNF691-low versus ZNF691-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF691→partner) and Y-score (partner→ZNF691) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADAdipocytes →+0.047+3.352.002.01631
COADEosinophils →+0.066+3.605.023.00831
UCECTh2 cells →+0.175+2.000.031.03231
UCECClass-switched memory B-cells →-0.056-2.700.030.00621
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Adipocytes by ZNF691 expression — COAD

Box plot of Adipocytes in ZNF691-low vs ZNF691-high samples in COAD.

Explore this box plot interactively →

Exploration