ZNF691

Across TCGA cell cohorts, ZNF691 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF691-associated genes across cancer lineages are AVP, UTF1, and FAM205A. Each is linked with ZNF691 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF691-to-partner and partner-to-ZNF691 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by ZNF691-low versus ZNF691-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF691→partner) and Y-score (partner→ZNF691) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AVP →	+0.041	+3.217	<.001	.006	3	1
LARGE_INTESTINE	UTF1 →	+0.017	+3.217	<.001	.006	3	1
LARGE_INTESTINE	FAM205A →	+0.015	+4.029	.005	.001	3	1
BLOOD_Leukemia	CRYBB3 →	+0.107	+4.152	<.001	.009	3	1
BLOOD_Leukemia	CFHR5 →	+0.004	+4.969	<.001	.003	3	1
BLOOD_Leukemia	DMRTC2 →	+0.036	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

AVP by ZNF691 expression — LARGE_INTESTINE

Explore this box plot interactively →