ZNF684

Across TCGA patient cohorts, ZNF684 mutation is significantly associated with the RNA expression of many other genes, with 859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF684-associated genes across cancer lineages are RN7SL248P, LINC02654, and RNU7-53P. Each is linked with ZNF684 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF684-to-partner and partner-to-ZNF684 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by ZNF684-low versus ZNF684-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF684→partner) and Y-score (partner→ZNF684) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.091	+3.815	<.001	<.001	3	2
SKCM	LINC02654 →	+0.028	+3.990	<.001	.009	3	2
BLCA	RNU7-53P →	+0.778	+7.640	<.001	.009	3	2
BLCA	CYP3A54P →	+0.413	+7.640	<.001	.009	3	2
UCEC	MIR520H →	+0.193	+3.167	<.001	.005	3	2
UCEC	HMGN1P32 →	+0.191	+2.729	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 859 associations by consensus.

RN7SL248P by ZNF684 expression — UCEC

Explore this box plot interactively →