Across TCGA patient cohorts, ZNF682 mutation is significantly associated with the RNA expression of many other genes, with 3,687 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF682-associated genes across cancer lineages are SNORD30, SPZ1, and NDUFB4P4. Each is linked with ZNF682 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF682-to-partner and partner-to-ZNF682 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF682→partner) and Y-score (partner→ZNF682) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNORD30 →	+1.120	+4.513	<.001	.005	3	2
HNSC	SPZ1 →	+0.429	+3.742	<.001	.006	3	2
HNSC	NDUFB4P4 →	+0.540	+4.090	.002	.002	3	2
BLCA	RNU1-20P →	+0.396	+3.877	.004	.004	3	2
UCEC	C16orf95 →	+0.370	+2.392	<.001	<.001	3	2
UCEC	RANGAP1 →	+0.487	+2.895	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,687 associations by consensus.

Exploration

ZNF682 survival (RNA) · tumor vs normal (RNA) · all ZNF682 data types