Across TCGA patient cohorts, ZNF681 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,791 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF681-associated proteins across cancer lineages are PPP4R3A, MDC1, and PRPF4B. Each is linked with ZNF681 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF681-to-partner and partner-to-ZNF681 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF681→partner) and Y-score (partner→ZNF681) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP4R3A →	+0.217	+0.722	.007	.001	3	4
LSCC	MDC1 →	+0.322	+0.671	<.001	.001	3	4
LSCC	PRPF4B →	+0.275	+0.845	<.001	<.001	3	3
BRCA	ZSCAN18 →	+0.417	+0.524	<.001	.001	3	3
LSCC	NELFE →	+0.185	+0.636	.005	.003	3	3
BRCA	MOCS3 →	+0.389	+0.545	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,791 associations by consensus.

Exploration

ZNF681 survival (RNA) · tumor vs normal (RNA) · all ZNF681 data types