Across TCGA cell cohorts, ZNF681 RNA expression is significantly associated with the RNA expression of many other genes, with 10,362 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF681-associated genes across cancer lineages are ZNF675, ZNF429, and ZNF726. Each is linked with ZNF681 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZNF681-to-partner and partner-to-ZNF681 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF681→partner) and Y-score (partner→ZNF681) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	ZNF675 →	+1.675	+1.296	<.001	<.001	3	18
LIVER	ZNF429 →	+1.654	+1.209	<.001	<.001	3	17
LUNG_NSCLC_LUSC	ZNF726 →	+2.516	+1.369	<.001	<.001	3	17
BONE	ZNF66 →	+1.513	+1.171	<.001	<.001	3	17
LUNG_SCLC	ZNF682 →	+1.993	+1.378	<.001	<.001	3	16
BONE	ZNF43 →	+2.242	+0.935	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,362 associations by consensus.

Exploration

ZNF681 survival (RNA) · tumor vs normal (RNA) · all ZNF681 data types