Across TCGA patient cohorts, ZNF679 mutation is significantly associated with the RNA expression of many other genes, with 2,563 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF679-associated genes across cancer lineages are SEC61GP1, DCP1A, and MIR6870. Each is linked with ZNF679 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF679-to-partner and partner-to-ZNF679 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF679→partner) and Y-score (partner→ZNF679) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SEC61GP1 →	+0.490	+4.602	<.001	.008	3	2
UCEC	DCP1A →	+0.623	+2.743	<.001	.002	3	2
UCEC	MIR6870 →	+0.292	+2.344	.002	.002	3	2
UCEC	CASTOR2 →	+0.721	+1.797	<.001	.008	3	2
SKCM	LDHAP2 →	+0.411	+2.019	.006	.005	3	2
LIHC	LINC00440 →	+0.074	+5.268	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,563 associations by consensus.

Exploration

ZNF679 survival (RNA) · tumor vs normal (RNA) · all ZNF679 data types