Across TCGA patient cohorts, ZNF679 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF679-associated genes across cancer lineages are eEF2, JNK_pT183_Y185, and JNK2. Each is linked with ZNF679 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF679-to-partner and partner-to-ZNF679 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF679→partner) and Y-score (partner→ZNF679) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.319	+2.999	.026	.035	3	2
UCEC	JNK_pT183_Y185 →	-0.176	-3.459	.009	.005	3	2
UCEC	JNK2 →	+0.170	+1.906	.033	.016	3	2
LUSC	HER2_pY1248 →	+0.358	+2.179	.003	.035	3	1
LUSC	Cyclin-B1 →	+0.555	+2.179	.008	.035	2	2
LUSC	Cyclin-E2 →	+0.149	+2.179	.013	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

ZNF679 survival (RNA) · tumor vs normal (RNA) · all ZNF679 data types