Across TCGA patient cohorts, ZNF676 mutation is significantly associated with the RNA expression of many other genes, with 4,875 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF676-associated genes across cancer lineages are ALYREF, LINC02525, and HROB. Each is linked with ZNF676 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF676-to-partner and partner-to-ZNF676 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF676→partner) and Y-score (partner→ZNF676) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ALYREF →	+0.445	+1.784	.004	<.001	3	4
HNSC	LINC02525 →	+0.961	+2.606	<.001	.001	3	4
LUAD	HROB →	+0.517	+2.240	.007	.005	3	4
LUSC	NFU1 →	+0.316	+2.727	.009	.003	3	4
UCEC	MED27 →	+0.351	+1.848	<.001	<.001	3	4
UCEC	NDUFAB1 →	+0.362	+2.556	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,875 associations by consensus.

Exploration

ZNF676 survival (RNA) · tumor vs normal (RNA) · all ZNF676 data types