Across TCGA cell cohorts, ZNF676 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF676-associated genes across cancer lineages are H2BC1, H2AC1, and KRTAP10-1. Each is linked with ZNF676 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF676-to-partner and partner-to-ZNF676 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF676→partner) and Y-score (partner→ZNF676) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	H2BC1 →	+0.433	+5.977	<.001	.001	3	1
SOFT_TISSUE	H2AC1 →	+0.193	+5.977	<.001	.001	3	1
SOFT_TISSUE	KRTAP10-1 →	+0.034	+5.369	.002	.004	3	1
SOFT_TISSUE	GAGE12E →	+0.090	+4.930	<.001	.008	3	1
LARGE_INTESTINE	DNAJA2 →	+0.517	+3.082	.003	.007	3	1
LUNG_NSCLC_LUAD	CPXCR1 →	+0.174	+4.169	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

ZNF676 survival (RNA) · tumor vs normal (RNA) · all ZNF676 data types