Across TCGA cell cohorts, ZNF676 mutation is significantly associated with the mutation status of many other genes, with 4,438 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF676-associated genes across cancer lineages are MAST4, EML5, and GUCY2F. Each is linked with ZNF676 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF676-to-partner and partner-to-ZNF676 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF676→partner) and Y-score (partner→ZNF676) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MAST4 →	+3.651	+4.777	.002	.002	1	5
SKIN	EML5 →	+3.718	+3.053	.006	.006	1	5
CNS	GUCY2F →	+5.614	+5.044	.003	.003	1	5
OVARY	PRRC2B →	+3.421	+4.009	<.001	<.001	1	5
LARGE_INTESTINE	SLC9C2 →	+2.471	+2.369	.005	.005	1	5
PANCREAS	NCOR1 →	+5.115	+5.115	.005	.005	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,438 associations by consensus.

Exploration

ZNF676 survival (RNA) · tumor vs normal (RNA) · all ZNF676 data types