ZNF674

Across TCGA patient cohorts, ZNF674 mutation is significantly associated with the RNA expression of many other genes, with 2,321 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF674-associated genes across cancer lineages are RNA5SP413, RN7SKP43, and RN7SKP221. Each is linked with ZNF674 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF674-to-partner and partner-to-ZNF674 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by ZNF674-low versus ZNF674-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF674→partner) and Y-score (partner→ZNF674) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+0.764	+1.469	<.001	.006	3	2
GBM	RN7SKP43 →	+0.231	+5.352	<.001	.005	3	2
BRCA	RN7SKP221 →	+0.099	+8.471	<.001	.005	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1
GBM	LINC02719 →	+0.184	+5.352	<.001	.005	3	1
GBM	LINC02745 →	+0.222	+5.352	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,321 associations by consensus.

RNA5SP413 by ZNF674 expression — UCEC

Explore this box plot interactively →