ZNF671

Across TCGA patient cohorts, ZNF671 mutation is significantly associated with the RNA expression of many other genes, with 1,330 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF671-associated genes across cancer lineages are SLC25A52, RNA5SP452, and RPS27P1. Each is linked with ZNF671 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF671-to-partner and partner-to-ZNF671 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A52 grouped by ZNF671-low versus ZNF671-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF671→partner) and Y-score (partner→ZNF671) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	SLC25A52 →	+0.237	+3.807	<.001	.008	3	2
READ	RNA5SP452 →	+0.537	+3.724	<.001	.007	3	2
READ	RPS27P1 →	+0.192	+5.096	<.001	.002	3	2
READ	H2BP6 →	+0.304	+4.142	<.001	.004	3	2
BRCA	VN1R79P →	+0.065	+4.341	<.001	.009	3	2
UCEC	MIR4539 →	+0.650	+1.870	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,330 associations by consensus.

SLC25A52 by ZNF671 expression — READ

Explore this box plot interactively →