ZNF662

Across TCGA patient cohorts, ZNF662 mutation is significantly associated with the RNA expression of many other genes, with 4,133 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF662-associated genes across cancer lineages are RNA5SP213, MT1HL1, and MIR8086. Each is linked with ZNF662 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF662-to-partner and partner-to-ZNF662 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP213 grouped by ZNF662-low versus ZNF662-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF662→partner) and Y-score (partner→ZNF662) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP213 →	+0.349	+2.265	<.001	.009	3	3
COAD	MT1HL1 →	+0.606	+4.342	<.001	.001	3	2
COAD	MIR8086 →	+0.305	+4.392	<.001	.006	3	2
ESCA	RN7SKP144 →	+0.114	+5.247	.004	.006	3	2
SKCM	OR52X1P →	+0.020	+2.512	.003	.008	3	2
SKCM	CORT →	+0.388	+3.234	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,133 associations by consensus.

RNA5SP213 by ZNF662 expression — UCEC

Explore this box plot interactively →