ZNF662

Across TCGA pan-cancer cohorts, ZNF662 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ZNF662 data layer compared with 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ZNF662 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF662 expression acts as an unfavorable survival marker, although some lineages such as HNSC and KIRP show a favorable association.

HNSC, STAD, and KIRP are the cancer types where ZNF662 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.670	0.537	<.001	132	view →
STAD	OS	Median	All	0.505	0.656	.001	78	view →
KIRP	DFS	Median	All	0.963	0.854	<.001	69	view →
UCS	DFS	Tertile	III,IV	0.690	0.280	.003	62	view →
LGG	DFS	Median	All	0.617	0.859	<.001	51	view →
THYM	DFS	Median	III,IV	1.000	0.480	.010	25	view →
LUAD	OS	Median	All	0.855	0.713	.001	24	view →
UCEC	DFS	Quartile	All	0.776	0.868	.012	12	view →
ESCA	DFS	Median	All	0.574	0.415	.021	11	view →
LIHC	DFS	Quartile	III,IV	0.394	0.193	.014	7	view →
ACC	DFS	Median	All	0.753	0.469	.008	5	view →
READ	OS	Tertile	IV	1.000	0.599	.033	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ZNF662–HNSC (DFS)

Open the HNSC breakdown →