Across TCGA patient cohorts, ZNF662 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF662-associated genes across cancer lineages are Notch1, p38-MAPK_pT180_Y182, and ATM. Each is linked with ZNF662 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF662-to-partner and partner-to-ZNF662 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF662→partner) and Y-score (partner→ZNF662) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.147	+1.594	.001	.021	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.447	-2.087	.002	.005	3	2
UCEC	ATM →	-0.383	-1.415	.011	.043	3	2
UCEC	4E-BP1 →	+0.298	+3.807	.001	<.001	3	2
UCEC	GSK-3_pS9 →	-0.378	-1.807	.005	.024	3	1
UCEC	JNK2 →	+0.149	+1.321	.025	.029	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

ZNF662 survival (RNA) · tumor vs normal (RNA) · all ZNF662 data types