ZNF662

Across TCGA cell cohorts, ZNF662 mutation is significantly associated with the RNA expression of many other genes, with 218 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF662-associated genes across cancer lineages are HM13, CRYM, and WRAP73. Each is linked with ZNF662 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF662-to-partner and partner-to-ZNF662 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HM13 grouped by ZNF662-low versus ZNF662-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF662→partner) and Y-score (partner→ZNF662) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HM13 →	-0.513	-3.278	.009	.006	3	1
LARGE_INTESTINE	CRYM →	+1.145	+3.364	.001	.002	3	1
LARGE_INTESTINE	WRAP73 →	+0.608	+3.364	.001	.002	3	1
LARGE_INTESTINE	KDSR →	+0.715	+3.364	.004	.002	3	1
LARGE_INTESTINE	METTL8 →	+0.907	+3.364	<.001	.002	3	1
LARGE_INTESTINE	TOX2 →	+1.423	+3.364	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 218 associations by consensus.

HM13 by ZNF662 expression — LARGE_INTESTINE

Explore this box plot interactively →