ZNF658

Across TCGA patient cohorts, ZNF658 protein abundance is significantly associated with the RNA expression of many other genes, with 793 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF658-associated genes across cancer lineages are DUSP29, DUX4L50, and CCDC22. Each is linked with ZNF658 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF658-to-partner and partner-to-ZNF658 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF658 versus DUSP29 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF658→partner) and Y-score (partner→ZNF658) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DUSP29 →	+0.160	+0.417	.005	.003	3	2
PDAC	DUX4L50 →	+1.212	+0.520	.008	.006	3	2
PDAC	CCDC22 →	-0.428	-0.451	.001	.006	3	1
PDAC	SLC35A2 →	-0.551	-0.520	<.001	<.001	3	1
PDAC	RP2 →	-0.614	-0.551	.005	.006	3	1
PDAC	TRPS1 →	+0.594	+0.446	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 793 associations by consensus.

ZNF658 vs DUSP29 — GBM

Explore this scatter interactively →