ZNF658

Across TCGA patient cohorts, ZNF658 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,551 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF658-associated proteins across cancer lineages are RABL6_T599, RAPGEF2_S935, and RBM33_S481. Each is linked with ZNF658 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF658-to-partner and partner-to-ZNF658 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF658 versus RABL6_T599 in PDAC, with a Pearson correlation of -0.56.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF658→partner) and Y-score (partner→ZNF658) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RABL6_T599 →	-0.712	-0.567	.002	.001	3	1
PDAC	RAPGEF2_S935 →	-0.493	-0.440	.009	.004	3	1
PDAC	RBM33_S481 →	-0.798	-0.574	.003	.002	3	1
GBM	ZC3H13_S381 →	-0.874	-0.612	.004	.001	3	1
GBM	ZNF148_S665 →	+0.579	+0.731	.002	<.001	3	1
UCEC	ZBTB21_S516 →	-0.464	-0.697	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,551 associations by consensus.

ZNF658 vs RABL6_T599 — PDAC

Explore this scatter interactively →