ZNF658

Across TCGA patient cohorts, ZNF658 mutation is significantly associated with the RNA expression of many other genes, with 2,342 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF658-associated genes across cancer lineages are RNU6-766P, CEP19P1, and PRR29. Each is linked with ZNF658 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF658-to-partner and partner-to-ZNF658 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-766P grouped by ZNF658-low versus ZNF658-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF658→partner) and Y-score (partner→ZNF658) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNU6-766P →	+0.589	+5.352	<.001	.005	3	3
GBM	CEP19P1 →	+0.168	+5.352	<.001	.005	3	3
UCEC	PRR29 →	-0.789	-1.807	.003	<.001	3	3
LUAD	RN7SL703P →	+0.131	+3.332	<.001	.005	3	3
UCEC	MVD →	+0.680	+1.839	<.001	<.001	3	3
UCEC	PAPLN →	-0.631	-2.376	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,342 associations by consensus.

RNU6-766P by ZNF658 expression — GBM

Explore this box plot interactively →