ZNF653

Across TCGA patient cohorts, ZNF653 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,149 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF653-associated proteins across cancer lineages are RAVER1, ILF2, and KDM1A. Each is linked with ZNF653 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF653-to-partner and partner-to-ZNF653 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF653 versus RAVER1 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF653→partner) and Y-score (partner→ZNF653) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RAVER1 →	+0.449	+0.679	<.001	<.001	3	6
OV	ILF2 →	+0.305	+0.470	.004	.009	3	5
GBM	KDM1A →	+0.350	+0.507	<.001	<.001	3	5
OV	TMEM87B →	-0.479	-0.519	<.001	<.001	3	5
OV	PIN1 →	+0.393	+0.401	<.001	<.001	3	5
LSCC	ILF3 →	+0.280	+0.479	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,149 associations by consensus.

ZNF653 vs RAVER1 — OV

Explore this scatter interactively →